14 Jun 2016

Off-site administration

Off-site administration policy for designated Yellow Fever Vaccination Centres (YFVCs) in England, Wales and Northern Ireland Off-site administration

In exceptional circumstances, YF vaccine may need to be administered at a site other than a designated YFVC (known as off-site administration). Exceptional circumstances for off-site administration may include a mobile occupational health unit providing services to industry, or vaccine administered on school premises not designated as a YFVC. Home visits are not normally considered to be an exceptional circumstance. All such exceptional circumstances will be evaluated by NaTHNaC on an individual basis. 

All YFVCs wishing to arrange off-site YF vaccine administration must complete an application form.

YFVCs should allow at least two working weeks from receipt for this to be processed by NaTHNaC.

Off-site administration policy for designated YFVCs

In order to assure the quality and safety of yellow fever vaccine administration, yellow fever vaccine can only be given at centres that have been designated. Under International Health Regulations (2005) it is the role of an individual country to regulate and ensure these standards are met. In England, Wales and Northern Ireland this falls to NaTHNaC. NaTHNaC assumed responsibility for the administration of YFVCs from the Department of Health in July 2003. Because yellow fever vaccine falls under International Health Regulations (2005), the rules surrounding its administration are stricter than for other vaccines.

In the majority of circumstances, travellers who need yellow fever vaccine attend the premises of a designated YFVC in order to receive their vaccine. In the UK this is usually a GP surgery, occupational health unit or specialist travel clinic.

There may be exceptional circumstances when yellow fever vaccine will need to be administered at a site other than the designated YFVC; immunisation away from the YFVC is discouraged. Exceptional circumstances for ‘offsite’ administration may include a mobile occupational health unit providing services to industry, or vaccine administered on school premises not designated as YFVCs. Home visits are not normally considered to be an exceptional circumstance. All such exceptional circumstances will be evaluated by NaTHNaC on an individual basis.

Offsite administration of yellow fever vaccine should comply with the following regulations:

  • The ‘party’ providing and administering the yellow fever vaccine must be a designated YFVC

  • All conditions of designation must be adhered to

  • YF vaccine should be stored within a YFVC

  • Administration of vaccine will take place as it would within the premises of a YFVC, e.g.

- the cold chain is maintained
- resuscitation equipment is available
- consent is obtained
- the International Certificate of Vaccination or Prophylaxis (ICVP) is completed accurately (the ICVP can be signed by children over 16 years of age)
- vaccine and sharps are disposed of safely

  • Records of vaccination should be stored within a YFVC

It should be remembered that all practitioners are professionally accountable for their practice.

All YFVCs that wish to vaccinate away from their premises must request to do so from NaTHNaC in writing.



Off-site administration of yellow fever vaccine (hospital setting)

Exceptionally, it may be appropriate for a traveller to receive YF vaccine in a hospital setting, which may not have designated YFVC status.

All YFVCs that wish to arrange for YF vaccine to be administered away from their premises in a hospital setting should discuss with a nurse advisor at NaTHNaC. Please either:


NaTHNaC cannot arrange for vaccine to be administered in a hospital setting. YFVCs are required to adhere to a protocol regarding any such arrangement, which will be explained as part of the enquiry process. 

Please note, NaTHNaC requires a minimum of five working days to process applications for off-site administration in a hospital setting. Administration in a hospital setting (where possible) can take time to arrange, and is the responsibility of the YFVC. Please consider this when counselling the traveller.

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